From my little experience I'd say:
No 3 is exclusive for things like Avics, where every time you open the top lid you destroy the web tube.
Arboreal spiders tend to run upwards for escaping, which makes the top lid fun, but also useful. I use the bag method to rehouse or remove them for major maintenance, so for me up is good.
I like cross ventilation with a vent low down and one higher up on the opposite side or on top. Different gasses have different mass, so to my little wet mind it seems ideal to have a situation where there is a place for the heavier gasses to escape.
Good luck!
I'm not impossible. I'm being improbable.